LDL-receptor gene polymorphism as a predictor of coronary artery disease: an Egyptian pilot study: relation to lipid profile and angiographic findings

The Egyptian Heart Journal

Table 2 Allele frequencies in cases versus the control

Allele	N (%)			Chi-square test			Binary logistic regression
Allele	Control	Case (CAD)	Total	χ²	Phi (ϕ)	p value	COR	95% CI	p value
G	60 (30%)	36 (18%)	96 (24%)	7.895	0.140	0.005	r(1) 1.95	r(1) 1.2–3.1	0.005
T	140 (70%)	164 (82%)	304 (76%)	7.895	0.140	0.005	r(1) 1.95	r(1) 1.2–3.1	0.005

Bold value indicate significance p ≤ 0.050
CAD coronary artery disease, COR crude odds ratio, CI confidence interval
r(1) = reference category
This table shows a statistically significantly higher proportion of ‘T’ allele among cases versus control (risk allele). This association is of low strength (ϕ lies between 0.1 and 0.3). A participant with ‘T’ allele has 1.95 times higher odds to exhibit CAD versus a participant with ‘G’ allele