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The Egyptian Heart Journal

Table 7 Regression analysis for prediction of CAD susceptibility

From: LDL-receptor gene polymorphism as a predictor of coronary artery disease: an Egyptian pilot study: relation to lipid profile and angiographic findings

 

Univariable

Multivariable

P

OR

95% CI

p

OR

95% CI

Age

0.149

1.016

0.994

1.038

    

Gender

0.107

0.720

0.483

1.074

    

Smoking

< 0.001

3.605

2.413

5.387

0.767

1.012

0.935

1.095

BMI

< 0.001

1.116

1.064

1.170

0.021

1.008

1.001

1.014

HTN

< 0.001

1.885

1.486

2.390

< 0.001

1.874

1.722

2.040

Total Cholesterol

< 0.001

1.056

1.041

1.071

0.002

1.003

1.001

1.006

TG

< 0.001

1.027

1.020

1.034

0.649

1.001

0.999

1.002

HDL-C

0.111

0.988

0.973

1.003

    

LDL-C

< 0.001

1.051

1.038

1.064

0.192

0.999

0.996

1.001

GT

< 0.001

4.071

2.187

7.579

< 0.001

1.194

1.108

1.288

TT

< 0.001

15.043

7.838

28.873

0.025

1.076

1.009

1.148

GT + TT

< 0.001

7.360

4.099

13.215

0.035

1.994

1.777

1.541

T

< 0.001

4.241

3.224

5.578

< 0.001

2.364

1.988

3.595

  1. Bold value indicate significance p ≤ 0.050
  2. As shown in this table, Logistic regression analysis is conducted for prediction of CAD susceptibility, using age, gender, residence, smoking, BMI, hypertension, TC, TG, HDL-C, LDL-C, rs1122608genotypes, alleles, dietary patterns as covariates. Higher frequency of smoking, hypertension, GT, TT, GT + TT, genotypes, T allele, unhealthy dietary pattern, higher levels of BMI, TC, TG, LDL-C,, lower frequency of healthy dietary pattern are considered as risk factors for CAD in univariable analysis.While, healthy dietary pattern is protective for CAD (p < 0.001, OR = 0.206, 95% CI 0.140–0.305)
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