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Table 4 Comparison of patients with right ventricular dysfunction and those with normal right ventricular function regarding echocardiographic findings

From: Prognostic significance of right ventricular dysfunction in patients presenting with acute left-sided heart failure

Variables

No RVD Number (%) or mean ± SD (n = 88)

RVD Number (%) or mean ± SD (n = 86)

P value

Left heart size

LVEDD (mm)

57.3 ± 9.9

62.3 ± 9.6

0.001

LVESD (mm)

45.4 ± 9.9

52.2 ± 9.4

 < 0.001

SWT (mm)

9.8 ± 1.9

9.0 ± 2.1

0.004

PWT (mm)

9.7 ± 1.6

9.1 ± 1.9

0.04

LV EDV (ml)

151.4 ± 65.3

189 ± 55.4

 < 0.001

LV ESV (ml)

101.7 ± 53.6

138.1 ± 48.3

 < 0.001

LA ESV (ml)

58 ± 27.2

80.3 ± 28.4

 < 0.001

LV function

EF % (Simpson)

34.9 ± 8.1

27.8 ± 7.9

 < 0.001

E/A

1.27 ± 0.7

2.2 ± 0.9

 < 0.001

RWMA IVS

84 (96.6)

86 (100)

0.25

Hypokinetic

23 (26.1)

31 (36)

0.003

Akinetic

58 (65.9)

42 (58.8)

 

Dyskinetic

3 (3.4)

13 (15.1)

 

RWMA Overall

88 (100)

86 (100)

1.0

Hypokinetic

22 (25)

28 (32.6)

0.017

Akinetic

62 (70.5)

45 (52.3)

 

Dyskinetic

4 (4.5)

13 (15.1)

 

Right heart size

RVWT (PLAX) (mm)

4.2 ± 0.7

4.4 ± 0.8

0.12

RVWT (subcostal) (mm)

4.6 ± 0.8

4.8 ± 1.0

0.11

RVOT (PLAX) (mm)

31.5 ± 4.9

37.4 ± 5.9

 < 0.001

RVOT 1 (mm)

31.2 ± 4.7

36.9 ± 5.6

 < 0.001

RVOT 2 (mm)

25.9 ± 3.6

28.7 ± 4.6

 < 0.001

Main PA (mm)

22.1 ± 3.6

24 ± 4.1

0.003

RVD 1 (mm)

36.6 ± 6.8

46.5 ± 9

 < 0.001

RVD 2 (mm)

24.9 ± 6.0

34 ± 8.1

 < 0.001

RVD 3 (mm)

71.2 ± 11.2

79.4 ± 8.3

 < 0.001

RV EDA (cm2)

18.7 ± 7.1

27.6 ± 7.3

 < 0.001

RV ESA (cm2)

10.3 ± 5.2

20.6 ± 6.4

 < 0.001

RA width (mm)

35.1 ± 6.5

44.4 ± 9.8

 < 0.001

RA length (mm)

43.5 ± 8.3

51.3 ± 10.1

 < 0.001

RA area (cm2)

14.1 ± 4.9

21.2 ± 7.4

 < 0.001

RVH

7 (8)

10 (11.6)

0.42

Dilated RVOT

38 (44.7)

75 (87.2)

 < 0.001

Dilated RV

13 (14.8)

57 (66.3)

 < 0.001

Dilated RVOT & RV

42 (47.7)

75 (87.2)

 < 0.001

RV function

TAPSE (mm)

20.7 ± 5.8

12.7 ± 3.6

 < 0.001

RV S' (cm/s)

12.4 ± 2.3

8.2 ± 2.3

 < 0.001

RV FAC

46.3 ± 8.9

25.2 ± 7.5

 < 0.001

RVD

0

86 (100)

 < 0.001

RVD & Dilated RV

0

57 (66.3)

 < 0.001

RVD & Dilated RVOT & RV

0

72 (83.7)

 < 0.001

RIMP

0.47 ± 0.05

0.72 ± 0.19

 < 0.001

RV FWS

− 21.3 ± 7.8

− 13.2 ± 5.8

 < 0.001

RV GLS

− 15.7 ± 6.9

− 10.8 ± 5.2

 < 0.001

Estimated right-sided pressures

RVSP (mmHg)

34.4 ± 13.1

39.9 ± 13.1

0.03

EPASP (mmHg)

42.4 ± 14.7

51.4 ± 14.3

0.001

RAP (mmHg)

6.4 ± 4.7

10.8 ± 5.3

 < 0.001

IVCEXP (mm)

17.4 ± 6.6

22.1 ± 6.9

 < 0.001

IVCINS (mm)

7.1 ± 9.2

15.2 ± 10.8

 < 0.001

Valvular abnormalities

Tricuspid regurgitation

 None

21 (24.7)

6 (7)

 < 0.001

 Mild

45 (53)

32 (37.2)

 Moderate

13 (15.3)

22 (25.6)

 Severe

6 (7.1)

26 (30.2)

Mitral regurgitation

 None

14 (16.1)

4 (4.7)

 < 0.001

 Mild

44 (50.5)

24 (27.9)

 Moderate

20 (20.3)

23 (26.7)

 Severe

9 (10.3)

35 (40.7)

Mitral Stenosis

 None

87 (98.9)

84 (97.7)

0.6

 Mild

0

0

 Moderate

0

1 (1.2)

 Severe

1 (1.1)

1 (1.2)

Aortic regurgitation

 None

72 (81.8)

69 (80.2)

0.75

 Mild

16 (18.1)

16 (18.6)

 Moderate

0

1 (1.2)

 Severe

0

0

Aortic stenosis

 None

86 (97.7)

86 (100)

0.37

 Mild

2 (2.2)

0

 Moderate

0

0

 Severe

1 (1.1)

0

Pericardial effusion

 None

80 (90.9)

75 (87.2)

0.51

 Mild

8 (9.1)

10 (11.6)

 Moderate

0 (0)

1 (1.2)

 Severe

0

0

Intracardiac thrombus

11 (12.5)

5 (5.8)

0.13

  1. Significant P values are given in bold (P value < 0.05)
  2. LV: left ventricle; LVEDD: LV end-diastolic diameter; LVESD: LV end-systolic diameter; SWT: septal wall thickness; PWT: posterior wall thickness; EDV: end-diastolic volume; ESV: end-systolic volume; Ao: aorta; LA: left atrium; EF: ejection fraction; RWMA: regional wall motion abnormalities; IVS: interventricular septum; PLAX: parasternal long axis; RVOT: right ventricular outflow tract; RVOT 1: proximal RVOT diameter in the parasternal short axis view; RVOT 2: distal RVOT diameter in the parasternal short axis view; PA: pulmonary artery; RV: right ventricle; RVD 1: RV basal diameter; RVD 2: RV mid diameter; RVD 3: RV length; RVWT: RV wall thickness; EDA: end-diastolic area; ESA: end-systolic area; RA: right atrium; RVH: RV hypertrophy; TAPSE: tricuspid annular plane systolic excursion; S': tissue Doppler derived systolic excursion velocity; FAC: fractional area change; RVD: right ventricular dysfunction; RIMP: right ventricular index of myocardial performance; FWL: free wall longitudinal strain; GLS: global longitudinal strain; RVSP: RV systolic pressure; EPASP: estimated pulmonary artery systolic pressure; RAP: right atrial pressure; IVCEXP: inferior vena cava diameter during expiration; IVCINS: inferior vena cava diameter during inspiration