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Table 2 Estimation of persons in the general population at risk for elevated troponin levels (as a sign for myocardial damage) after COVID-19 vaccination compared to the risk of elevated troponin levels caused by SARS-CoV-2 infection

From: Commentary: raised c-troponin levels as a sign of myocardial injury after COVID-19 vaccination in healthy individuals are worrying

Country

Population*

Vaccinated against Covid 19

SARS-CoV2 cases in 2020**

Hospitalized according to National data in 2020**

Elevated troponin at > 14 ng/l in 1.8% of non-hospitalized cases

Elevated troponin at > 14 ng/l in 7% of the hospitalized Covid-19 patients

Elevated troponin, estimated at 20% of hospitalized

Elevated troponin > 13.5 ng/l (after vaccination) in 2.8% of the vaccinated population

Germany

84.4 million

83%: 70.384 million

1,782,948

137,333

32,093

9613

27467

1.97 million

Switzerland

8.7 million

69.76%:

6.07 million

454,197***

40,893

8175

2862

8179

169,960

  1. *According to official statistical data
  2. **source: Robert-Koch-Institute, data from 23rd June 2023, https://www.rki.de/DE/Content/InfAZ/N/Neuartiges_Coronavirus/Daten/Klinische_Aspekte.html (accessed 17th August 2023) and Swiss Office of Statistics (https://dam-api.bfs.admin.ch/hub/api/dam/assets/23771995/master accessed 17th August 2023)
  3. ***Our World in Data https://ourworldindata.org/covid-cases?country=GBR~CAN~DEU~FRA accessed 18th August 2023
  4. Elevated troponin levels after vaccination were estimated from the systematic observation of Buergin et al. and are given in the last column. The risk of elevated troponin levels in hospitalized and non-hospitalized persons with SARS-CoV-2 infection was derived from National data in Germany and Switzerland and the results reported by Niedziela et al. [5] and Mueller et al. [3], respectively