Impact of prosthesis oversizing on clinical outcomes of transcatheter aortic valve implantation using a self-expandable Evolut R valve

Elnwagy, Mohammed Moustafa; Baraka, Mahmoud Mohamed Ali; Hafez, Mohamed Saber; Kamal, Diaa; El-Sayed, Maiy Hamdy; Mostafa, Ahmad E.

doi:10.1186/s43044-024-00450-0

The Egyptian Heart Journal

Table 2 Showing the descriptive data, clinical, ECG, echocardiographic and CT parameters

From: Impact of prosthesis oversizing on clinical outcomes of transcatheter aortic valve implantation using a self-expandable Evolut R valve

Demographics		No. = 143
Age (years)	Female	60 (42.0%)
	Male	83 (58.0%)
Weight (Kg)	Mean ± SD	73.80 ± 6.55
	Range	55–88
Height (m)	Mean ± SD	79.30 ± 14.36
	Range	50–125
BMI (Kg/m²)	Mean ± SD	1.65 ± 0.08
	Range	1.5–1.82
BSA(m²)	Mean ± SD	29.07 ± 5.18
	Range	18.82–47.87
Age (years)	Mean ± SD	1.87 ± 0.18
	Range	1.44–2.39

Clinical data		No. = 143
CABG	No	130 (90.9%)
	Yes	13 (9.1%)
Euro score II %	Median (IQR)	3.45 (1.99–5.43)
	Range	0.84–40.2
STS PROM %	Median (IQR)	2.45 (1.73–3.54)
	Range	0.66–16.98
Smoking	Non-smoker	107 (74.8%)
	Smoker	25 (17.5%)
	EX -smoker	11 (7.7%)
DM	No	75 (52.4%)
	Yes	68 (47.6%)
HTN	No	33 (23.1%)
	Yes	110 (76.9%)
RHD	No	136(95.1%)
	Yes	7(4.9%)
IHD	No	87 (60.8%)
	Yes	56 (39.2%)
CVS	No	134 (93.7%)
	Yes	9 (6.3%)
CrCl (ml/min)	Mean ± SD	63.46 ± 26.73
	Range	9–161
CLD	No	132 (92.3%)
	Yes	11 (7.7%)

Electrocardiographic data		No. = 143
AF	No	117 (81.8%)
	Permanent	16 (11.2%)
	Paroxysmal	10 (7.0%)
PR interval (mm)	Mean ± SD	162.19 ± 36.11
	Range	0–200
QRS complex (mm)	Mean ± SD	88.67 ± 9.44
	Range	80–100
Echo-data		No. = 143
EF(%)	Mean ± SD	60.25 ± 13.14
	Range	20–84
SWT (mm)	Mean ± SD	12.64 ± 1.78
	Range	8–18
SWTi (mm/m²)	Mean ± SD	6.74 ± 1.17
	Range	0.51–9.8
PWT (mm)	Mean ± SD	12.25 ± 1.63
	Range	7–16
PWTi(mm/m²)	Mean ± SD	6.53 ± 1.13
	Range	0.51–9.8
LVEDD (mm)	Mean ± SD	50.35 ± 6.57
	Range	35–74
LVEDDi (mm/m²)	Mean ± SD	26.89 ± 4.76
	Range	0.51–46.54
LVESD (mm)	Mean ± SD	33.39 ± 7.49
	Range	20–63
LVESDi (mm/m²)	Mean ± SD	17.89 ± 4.73
	Range	0.51–37.73
PPG (mmHg)	Mean ± SD	81.82 ± 21.79
	Range	35–171
MPG (mmHg)	Mean ± SD	50.01 ± 13.80
	Range	20–100
AVA (cm²)	Median (IQR)	0.7 (0.5–0.8)
	Range	0.2–1
AVAi (cm²/m²)	Mean ± SD	0.38 ± 0.11
	Range	0.1–0.59
AR	0	15 (10.5%)
	1	86 (60.1%)
	2	38 (26.6%)
	3	4 (2.8%)
	4	(0.0%)
RVSP (mmHg)	Mean ± SD	42.01 ± 11.01
	Range	20–86
CT data		No. = 143
Annulus. Diameter (mm)	Mean ± SD	24.17 ± 1.73
	Range	20–28.4
Annulus. Diameter.indexed (mm/m²)	Mean ± SD	12.99 ± 1.40
	Range	8.93–17.48
Annulus. Perimeter (mm)	Mean ± SD	77.97 ± 5.09
	Range	69–92
Annulus. Perimeter. Indexed (mm/m²)	Mean ± SD	41.89 ± 4.33
	Range	34.17–56.6
Annulus. Area (mm²)	Mean ± SD	460.84 ± 62.79
	Range	339–666
Annulus. Area indexed (mm²/m²)	Mean ± SD	247.42 ± 37.40
	Range	166.91–377
LMCA.(mm)	Mean ± SD	12.96 ± 2.61
	Range	6.6–20.5
LMCAi (mm/m²)	Mean ± SD	6.96 ± 1.51
	Range	3.75–11.58
RCA.(mm)	Mean ± SD	14.95 ± 3.10
	Range	9.2–26.3
RCAi (mm/m²)	Mean ± SD	8.06 ± 1.94
	Range	4.62–14.85
MS.(mm)	Mean ± SD	8.82 ± 2.05
	Range	5–15.3
MS I (mm/m²)	Mean ± SD	4.76 ± 1.27
	Range	2.58–8.82
Grade of aortic Calcification	Grade 1	1	0.7%
	Grade 2	24	16.8%
	Grade 3	59	41.3%
	Grade 4	59	41.3%
Severe or non severe aortic Calcification	Grade 1–3	84	58.7%
	Grade 4	59	41.3%
Septal calcification	No	123	86.0%
	Yes	20	14.0%

AF Atrial fibrillation, AR Aortic regurgitation, AVA Aortic valve area, AVAi Aortic valve area indexed, BMI Body mass index, BSA Body surface area, Ca Calcification, CABG Coronary artery bypass graft, CLD Chronic lung disease, CrCl Creatinine clearance, CVS Cerebrovascular stroke, DM Diabetes mellitus, EF Ejection fraction, HTN Hypertension, IHD Ischemic heart disease, LVEDD Left ventricle end diastolic dimension, LVEDDi Left ventricle end diastolic dimension indexed, LVESD Left ventricle end systolic dimension, LVESDi Left ventricle end systolic dimension indexed, LMCA Left main coronary artery height, LMCAi Left main coronary artery height indexed, MPG Mean pressure gradient, MS Membranous septum, MSi Membranous septum indexed, PWT Posterior wall thickness, PWTi Posterior wall thickness indexed, PPG Peak pressure gradient, RCA Right coronary artery height, RCAi Right coronary artery height indexed, RHD Rheumatic heart disease, RVSP Right ventricular systolic pressure, STS PROM Society of thoracic surgery predicted risk of mortality, SWT Septal wall thickness, SWTi Septal wall thickness indexed

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