Impact of prosthesis oversizing on clinical outcomes of transcatheter aortic valve implantation using a self-expandable Evolut R valve

The Egyptian Heart Journal

Table 5 Comparison between group A and extreme oversizing group B regarding operative and post operative data

		Group A (< 20%)		Group B (> = 20%)		Test value	P-value	Sig.
		No.	%	No.	%	Test value
THV size	29.00	78	80.4%	31	67.4%	2.919*	0.088	NS
	34.00	19	19.6%	15	32.6%	2.919*	0.088	NS

Operative data		Group A (< 20%)	Group B (≥ 20%)	Test value	P-value	Sig.
Operative data		No. = 97	No. = 46	Test value	P-value	Sig.
DI (mm)	Median (IQR)	3.3 (2.7–5.2)	2.55 (1.6–3.7)	− 3.560‡	0.000	HS
	Range	1–8	1–8
DI I (mm/m²)	Median (IQR)	1.81 (1.44–2.75)	1.47 (0.82–1.88)	− 3.468‡	0.001	HS
	Range	0.47–4.6	0.42–4.42
Pre- implantation dilatation	No	73 (75.3%)	34 (73.9%)	0.030*	0.863	NS
	Yes	24 (24.7%)	12 (26.1%)
Post- implantation dilatation	No	80 (82.5%)	38 (82.6%)	0.000*	0.984	NS
	Yes	17 (17.5%)	8 (17.4%)
DIMS%	Median (IQR)	39.53 (28.39–61.39)	28.17 (18.89–45.54)	− 3.269	0.001	HS
	Range	10–114.23	10–76.19

ECG post operative		Group A (< 20%)		Group B (≥ 20%)		Test value*	P-value	Sig.
ECG post operative		No.	%	No.	%	Test value*	P-value	Sig.
Conduction Disturbance	No	74	76.3%	39	84.8%	1.358	0.2438	NS
	Yes	23	23.7%	7	15.2%
Permanent CHB	No	95	97.9%	46	100.0%	0.962	0.327	NS
	Yes	2	2.1%	0	0.0%
Transient Conduction. Disturbance	No	89	91.8%	43	93.5%	0.131	0.718	NS
	Yes	8	8.2%	3	6.5%
New LBBB	No	79	81.4%	40	87.0%	0.679	0.410	NS
	Yes	18	18.6%	6	13.0%
QRS widening	No	75	77.3%	39	84.8%	1.075	0.300	NS
	Yes	22	22.7%	7	15.2%
PR Prolongation	No	91	93.8%	46	100.0%	2.970	0.085	NS
	Yes	6	6.2%	0	0.0%
New onset AF	No	95	97.9%	45	97.8%	0.002	0.965	NS
	Yes	2	2.1%	1	2.2%

Postoperative data		Group A (< 20%)	Group B (≥ 20%)	Test value	P-value	Sig.
Postoperative data		No. = 97	No. = 46
PVL	No (0)	22 (22.7%)	39 (84.8%)	49.761*	0.000	HS
	Trivial (1)	61 (62.9%)	7 (15.2%)
	Mild (2)	12 (12.4%)	0 (0.0%)
	Moderate(3)	2 (2.1%)	0 (0.0%)
	Severe (4)	0 (0.0%)	0 (0.0%)
PVL	Non significnat	83 (85.6%)	46 (100.0%)	7.360*	0.007	HS
PVL	Significant 2–4	14 (14.4%)	0 (0.0%)	7.360*	0.007	HS
Coronary obstruction	No	97 (100.0%)	46 (100.0%)	NA	NA	NA

CHB Complete heart block, DIDO Depth of implantation derived oversizing index, DI Depth of implantation, DI Depth of implantation indexed, DIMS Depth of implantation to membranous septum ratio, LBBB Left bundle branch block, PVR Para-valvular leakage, THV Trans catheter heart valve
P-value > 0.05: Non significant (NS); P-value < 0.05: Significant (S); P-value < 0.01: highly significant (HS)
^‡Mann Whitney test
*Chi-square test
•Independent t-test