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The Egyptian Heart Journal

Table 6 Showing Comparison between populations without NOCD and populations with NOCD

From: Impact of prosthesis oversizing on clinical outcomes of transcatheter aortic valve implantation using a self-expandable Evolut R valve

 

No conduction dist

Conduction dist

Test value

P-value

Sig

  

No. = 113

No. = 30

Age (years)

Female

49 (43.4%)

11 (36.7%)

0.436*

0.509

NS

 

Male

64 (56.6%)

19 (63.3%)

   

Weight (kg)

Mean ± SD

73.75 ± 6.59

74.00 ± 6.53

 − 0.183•

0.855

NS

 

Range

55–88

60–83

   

Height (m)

Mean ± SD

79.49 ± 14.62

78.60 ± 13.55

0.301•

0.764

NS

 

Range

50–125

50–120

   

BMI(kg/m2)

Mean ± SD

1.64 ± 0.07

1.66 ± 0.08

 − 1.243•

0.216

NS

 

Range

1.5–1.82

1.5–1.82

   

BSA (m2)

Mean ± SD

29.28 ± 5.45

28.27 ± 3.94

0.949•

0.344

NS

 

Range

18.82–47.87

22.22–41.52

   

Age (years)

Mean ± SD

1.87 ± 0.18

1.89 ± 0.18

 − 0.626•

0.532

NS

 

Range

1.52–2.39

1.44–2.38

   

Euro score II %

Median (IQR)

3.35 (1.85–4.56)

4.67 (2.3–7.91)

 − 2.358‡

0.018

S

 

Range

0.84–40.2

0.91–13.98

   

STS score %

Median (IQR)

2.4 (1.75–3.2)

3.37 (1.57–4.56)

 − 2.066‡

0.039

S

 

Range

0.66–16.98

0.76–5.99

   

CABG

No

103 (91.2%)

27 (90.0%)

0.038*

0.846

NS

 

Yes

10 (8.8%)

3 (10.0%)

   

Smoking

Non-smoker

87 (77.0%)

20 (66.7%)

4.327*

0.115

NS

 

Smoker

20 (17.7%)

5 (16.7%)

   
 

EX -smoker

6 (5.3%)

5 (16.7%)

   

DM

No

63 (55.8%)

12 (40.0%)

2.359*

0.125

NS

 

Yes

50 (44.2%)

18 (60.0%)

   

HTN

No

26 (23.0%)

7 (23.3%)

0.001*

0.970

NS

 

Yes

87 (77.0%)

23 (76.7%)

   

IHD

No

75 (66.4%)

12 (40.0%)

6.920*

0.009

HS

 

Yes

38 (33.6%)

18 (60.0%)

   

CVS

No

109 (96.5%)

25 (83.3%)

6.926*

0.008

HS

 

Yes

4 (3.5%)

5 (16.7%)

   

CrCl (ml/mm2)

Mean ± SD

64.38 ± 27.42

60.00 ± 24.09

0.796•

0.427

NS

 

Range

9–161

12–117

   

CLD

No

105 (92.9%)

27 (90.0%)

0.285*

0.594

NS

 

Yes

8 (7.1%)

3 (10.0%)

   

Grade of aortic Calcification

Grade 1

0 (0.0%)

1 (3.3%)

5.091*

0.165

NS

 

Grade 2

21 (18.6%)

3 (10.0%)

   
 

Grade 3

47 (41.6%)

12 (40.0%)

   
 

Grade 4

45 (39.8%)

14 (46.7%)

   

Severe or non severe aortic Calcification

Grade 1–3

68 (60.2%)

16 (53.3%)

0.458*

0.499

NS

 

Grade 4

45 (39.8%)

14 (46.7%)

   

Septal Calcification

No

101 (89.4%)

22 (73.3%)

5.075*

0.024

S

 

Yes

12 (10.6%)

8 (26.7%)

   

Annulus. Diameter.indexed (mm/m2)

Mean ± SD

24.08 ± 1.71

24.50 ± 1.78

 − 1.172

0.243

NS

 

Range

20–28.2

22–28.4

   

Annulus. Perimeter (mm)

Mean ± SD

12.98 ± 1.45

13.01 ± 1.18

 − 0.120

0.905

NS

 

Range

8.93–17.48

10.71–17.01

   

Annulus. Perimeter. Indexed (mm/m2)

Mean ± SD

77.70 ± 4.93

78.97 ± 5.62

 − 1.210

0.228

NS

 

Range

69–90.1

70–92

   

Annulus. Area (mm2)

Mean ± SD

41.87 ± 4.42

41.98 ± 4.02

 − 0.121

0.904

NS

 

Range

34.17–56.6

34.45–52.08

   

Annulus. Area indexed (mm2/m2)

Mean ± SD

457.71 ± 59.77

472.49 ± 72.90

 − 1.146

0.254

NS

 

Range

339–615

379–666

   

Annulus. Diameter.indexed (mm/m2)

Mean ± SD

246.59 ± 37.62

250.50 ± 37.03

 − 0.507

0.613

NS

 

Range

166.91–377

200.87–348.69

   

DI (mm)

Median (IQR)

3 (2.2–3.7)

5.35 (3.5–7.22)

 − 3.560‡

0.000

HS

 

Range

1–7.19

1.3–8

   

DI I (mm/m2)

Median (IQR)

1.59 (1.16–1.96)

2.71 (1.92–3.68)

 − 3.468‡

0.001

HS

 

Range

0.42–4.05

0.76–4.6

   

DIMS %

Median (IQR)

33.72 (23.96–45.88)

69.26 (31.82–83.6)

 − 3.269‡

0.001

HS

 

Range

10–93.38

10–114.23

   

Pre implantation-Dilatation

No

84 (74.3%)

23 (76.7%)

0.068*

0.794

NS

 

Yes

29 (25.7%)

7 (23.3%)

   

Post- implantation Dilatation

No

95 (84.1%)

23 (76.7%)

0.901*

0.343

NS

 

Yes

18 (15.9%)

7 (23.3%)

   

RHD

No

110 (97.3%)

26 (86.7%)

5.807*

0.016

S

 

Yes

3 (2.7%)

4 (13.3%)

   

MS(mm)

Mean ± SD

8.76 ± 1.95

9.07 ± 2.43

 − 0.749•

0.455

NS

 

Range

5–14.4

5.3–15.3

   

MS i (mm/m2)

Mean ± SD

4.74 ± 1.21

4.87 ± 1.52

 − 0.500•

0.618

NS

 

Range

2.58–8.82

2.72–8.06

   

DIDO %

Mean ± SD

17.23 ± 5.79

13.98 ± 5.86

2.723•

0.007

HS

 

Range

0–30

1–23

   
  1. BMI Body mass index, BSA Body surface area, Ca Calcification, CABG Coronary artery bypass graft, CLD Chronic lung disease, CrCl Creatinine clearance, CVS Cerebrovascular stroke, DIDO Depth of implantation derived oversizing index, DI Depth of implantation, DI Depth of implantation indexed, DIMS Depth of implantation to membranous septum ratio, DM Diabetes mellitus, EF Ejection fraction, HTN Hypertension, IHD ischemic heart disease, MS Membranous septum, MSi Membranous septum indexed, RHD Rheumatic heart disease, STS PROM Society of thoracic surgery predicted risk of mortality
  2. P-value > 0.05: Non significant (NS); P-value < 0.05: Significant (S); P-value < 0.01: highly significant (HS)
  3. ‡Mann Whitney test *:Chi-square test; •: Independent t-test
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