| AUC | 95% CI | p value# | Cut-off | Sens. (%) | Spec. (%) | PPV (%) | NPV (%) |
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LA strain S-R(AVG) | 0.866 d | 0.789 to 0.943 |  < 0.001* |  ≤ 25 | 85.7 | 85.0 | 30.0 | 98.7 |
LA strain S-CD (AVG) | 0.899 c,d | 0.859 to 0.940 |  < 0.001* |  >  − 14 | 85.7 | 86.0 | 31.6 | 98.8 |
LA S-CT (AVG) | 0.813 b | 0.750 to 0.875 |  < 0.001* |  >  − 13 | 100.00 | 57.0 | 14.9 | 100.0 |
LA stiffness Index | 0.806 a,b | 0.705 to 0.906 |  < 0.001* |  > 0.39 | 85.71 | 84.95 | 30.0 | 98.7 |
- AUC, Area under ROC curve; CI, Confidence interval; #, p value from a test comparing AUC to the null hypothesis AUC of 0.5; Sens, Sensitivity; Spec., Specificity; PPV, Positive predictive value; NPV, Negative predictive value; S-R, Strain reservoir; S-CD, Strain conduit; S-CT, Strain contractile; AVG, Average
- *Significant at p < 0.05; a, Significant difference from LA strain S-R (AVG); b, Significant difference from LA strain S-CD (AVG); c, Significant difference from LA S-CT (AVG); d, Significant difference from LA stiffness