Table 8 Univariate and multivariate analysis of risk factors for the development of diastolic dysfunction in MAFLD patients
| Â | Univariate analysis | Multivariate analysis model | ||
|---|---|---|---|---|
p value | Unadjusted OR (95% CI) | p value | Adjusted OR (95% CI) | |
Age (years) | 0.755 | 0.987 (0.907–1.074) | – | – |
Male sex | 0.994 | 1.004 (0.372–2.706) | – | – |
DM |  < 0.001* | 21.048 (5.956–74.376) | 0.001* | 13.505 (2.863–63.696) |
BMI (kg/m2) | 0.055 | 0.865 (0.745–1.003) | 0.331 | 0.891 (0.706–1.125) |
Waist circumference (cm) | 0.776 | 0.993 (0.945–1.043) | – | – |
Total cholesterol | 0.049* | 1.030 (1.000–1.062) | 0.136 | 1.033 (0.990–1.078) |
LDL (mg/dL) | 0.113 | 1.019 (0.996–1.043) | – | – |
HDL (mg/dL) |  < 0.001* | 1.167 (1.081–1.259) | 0.001* | 1.231 (1.089–1.391) |
Triglycerides (mg/dL) | 0.094 | 0.987 (0.972–1.002) | 0.805 | 0.997 (0.970–1.024) |
Liver fibrosis | 0.097 | 1.589 (0.920–2.743) | 0.729 | 0.843 (0.320–2.220) |
Liver steatosis | 0.836 | 1.049 (0.665–1.656) | – | – |