Skip to main content

Table 1 Demographic and clinical data of the study group

From: Unlocking the potential of sacubitril/valsartan therapy in improving ECG and echocardiographic parameters in heart failure patients with reduced ejection fraction (HErEF)

Parameter

Result

Age (Yrs): mean ± SD

56.00 ± 8.22

Gender

Male, n (%)

78/100 (78%)

Female, n (%)

22/100 (22%)

BMI(Kg/m2): mean ± SD

24.76 ± 3.48

Risk factors & comorbidities

DM, n (%)

56/100 (56%)

Hypertension, n (%)

70/100 (70%)

Renal impairment, n (%)

18/100 (18%)

Dyslipidemia, n (%)

68/100 (68%)

Smoking, n (%)

62/100 (13%)

Alcoholic, n (%)

2/100 (2%)

OSA, n (%)

11/100 (11%)

Drug treatment

β Blockers, n (%)

100/100 (100%)

Loop diuretics, n (%)

88/100 (88%)

MRAs, n (%)

98/100 (98%)

SGLT2 inhibitor, n (%)

100/100 (100%)

Empagliflozin

19/100 (19%)

Dapagliflozin

81/100 (81%)

NYHA class

I, n (%)

13/100 (13%)

II, n (%)

55/100 (55%)

III, n (%)

32/100 (32%)

IV, n (%)

0

Echo parameters

LV EF (%)

31.59 ± 5.68

LVEDD (cm)

6.38 ± 0.62

LVESD (cm)

5.00 ± 0.83

LAD (cm)

4.59 ± 0.56

DD (≥ II grade)%

63/100 (63%)

Mitral regurgitation (MR) (≥ II grade) %

60/100 (60%)

ECG parameters

Heart rate (beats per minute)

78.14 ± 9.98

Atrial fibrillation (%)

23/100 (23%)

PR interval (ms)

138.53 ± 26.72

QRS width (ms)

123.70 ± 20.32

QTc interval (ms)

425.37 ± 32.86

T wave morphology changes (%)

74/100 (74%)

ST segment changes (%)

60/100 (60%)

QRS width

Wide ≥ 120 ms

69 (69%)

Narrow < 120 ms

13 (13%)

QRS morphology (in patients with wide QRS width)

LBBB

25 (25%)

RBBB

17 (17%)

IVCD

27 (27%)

  1. BMI, body mass index (kilogram/meter2); ICM, ischemic cardiomyopathy; NIDCM, non-ischemic dilated cardiomyopathy; DM, diabetes mellitus; OSA, obstructive sleep apnea; MI, myocardial infarction; PCI, percutaneous coronary intervention; CABG, Coronary artery bypass graft; VHD, valvar heart disease; MRAs, Aldosterone receptor antagonists;SGLT2 inhibitor, Sodium-glucose co-transporter 2 inhibitors; NYHA Class, New York Heart association classification; LV EF, left ventricular systolic ejection fraction; LVEDD, left ventricular end diastolic dimension; LVESD, left ventricular end systolic dimension; LAD, Left atrial dimension; DD, LV diastolic dysfunction; QTc interval, corrected QT interval; cm, centimeter; ms, millisecond; LBBB, left bundle branch block; RBBB, right bundle branch block; IVCD, intraventricular conduction delay