Table 3 Echocardiography parameters before and after the sacubitril/valsartan combination was initiated
Before S/V therapy | Six months after S/V therapy | Test value | p-value | |
|---|---|---|---|---|
LVEF (%) | ||||
Mean ± SD | 31.59 ± 5.68 | 34.44 ± 7.77 | 5.256** | 0.000 |
LVEDD (cm)) | ||||
Mean ± SD | 6.38 ± 0.62 | 6.08 ± 0.63 | − 8.657** | 0.000 |
LVESD (cm) | ||||
Mean ± SD | 5.00 ± 0.83 | 4.91 ± 0.79 | − 2.400** | 0.018 |
LAD (cm) | ||||
Mean ± SD | 4.59 ± 0.56 | 4.49 ± 0.48 | − 2.882** | 0.005 |
DD | ||||
Grade I | 21/100 (25.0%) | 26/100 (32.9%) | 10.188* | 0.006 |
Garde II | 36/100 (42.9%) | 44/100 (55.7%) | ||
Garde III | 27/100 (32.1%) | 9/100 (11.4%) | ||
MR | ||||
No | 4/100 (1.0%) | 6/100 (6.0%) | 6.711* | 0.243 |
Grade I | 36/100 (36.0%) | 33/100 (33.0%) | ||
Grade II | 54/100 (54.0%) | 53/100 (53.0%) | ||
Garde III/IV | 6/100 (6.0%) | 3/100 (3.0%) | ||