The outcome of genetic and non-genetic pediatric cardiomyopathies

AlAlakhfash, Ali; Agati, Luciano; Mazzesi, Giuseppe; Elhobi, Dalia; Alqwaiee, Abdullah; Alhory, Khalid; Almesned, Abdulrahman; Alhasnan, Zuhair; Alwadai, Abdullah

doi:10.1186/s43044-024-00473-7

The Egyptian Heart Journal

Table 4 DCM cases, comparison between those who are alive and dead

From: The outcome of genetic and non-genetic pediatric cardiomyopathies

		Alive	Died	Total	P-value	Odds ratio	Relative Risk
Gender	Male	56	24	80	0.568	1	1
Gender	Female	56	24	80	0.568	1	1
Mode of presentation	Heart failure	81	37	118	0.038
	Cardiogenic shock	18	11	29
	Asymptomatic	13	0	13
Primary or secondary	Primary	57	19	76	0.127	0.63	0.72
Primary or secondary	Secondary	55	29	84	0.127	0.63	0.72
Syndromic	Yes	9	5	14	0.415	1.33	1.21
Syndromic	No	103	43	146	0.415	1.33	1.21
Primary or secondary	Primary	53	19	4	0.483	0.62	0.72
Primary or secondary	Secondary	50	29	5	0.483	0.62	0.72
Suspected viral illness	Yes	22	2	24	0.008	0.18	0.25
Suspected viral illness	No	90	46	136	0.008	0.18	0.25
LV noncompaction	Yes	84	46	130	0.001	7.67	5.31
LV noncompaction	No	28	2	30	0.001	7.67	5.31
Consanguineous parents	Yes	32	26	58	0.002	2.95	2.08
Consanguineous parents	No	80	22	102	0.002	2.95	2.08
F/H of CMP	Yes	9	12	21	0.005	3.81	2.21
F/H of CMP	No	103	36	139	0.005	3.81	2.21
Genetic study	Positive/Abnormal	17	3	20	0.012
	Negative/Normal	35	6	41
	Pending	9	21	30
	Normal	51	18	69
Age of presentation	6 months or Less	40	22	62	0.152	1.52	1.34
Age of presentation	More than 6 months	72	26	98	0.152	1.52	1.34
Ejection fraction at presentation	20% or Less	10	25	35	< 0.001	11.09	3.88
Ejection fraction at presentation	More than 20%	102	23	125	< 0.001	11.09	3.88
Admission on first presentation	Yes	78	44	122	0.002	4.79	3.43
Admission on first presentation	No	34	4	38	0.002	4.79	3.43
ICU admission	Yes	51	29	5	0.045	2.27	1.81
ICU admission	No	40	10	0	0.045	2.27	1.81
IVIg administration	Yes	35	9	44	0.074	0.51	0.61
IVIg administration	No	77	39	116	0.074	0.51	0.61
ICU admission	Yes	57	32	89	0.047	1.93	1.6
ICU admission	No	55	16	71	0.047	1.93	1.6
Ventilation	Yes	74	21	95	0.007	0.4	0.53
Ventilation	No	38	27	65	0.007	0.4	0.53
Inotropes	Yes	70	21	91	0.022	0.47	0.59
Inotropes	No	42	27	69	0.022	0.47	0.59
Carvidolol	Yes	10	8	18	0.127	2.04	1.58
Carvidolol	No	102	40	142	0.127	2.04	1.58
Digoxin	Yes	39	16	55	0.503	1.22	1.14
Digoxin	No	73	32	105	0.503	1.22	1.14

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