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The Egyptian Heart Journal

Table 2 Comparison between the studied groups regarding miR-21 and miR-124 expression

From: Role of micro-RNAs 21, 124 and other novel biomarkers in distinguishing between group 1 WHO pulmonary hypertension and group 2, 3 WHO pulmonary hypertension

  

Group I

Group II

Group III

Control group

P value

No. = 30

No. = 20

No. = 18

No. = 20

MiR-21

Median (IQR)

2.45 (0.12–4.2)

0.18 (0.02–0.73)*

0.9 (0.1–1.1)**

0.27 (0.04–1.25)***

< 0.001

 

Range

0–3

0.01–1.43

0.04–1.84

0–2.22

 

MiR- 124

Median (IQR)

0.65 (0.27–1.23)

4.55a (2.5–6.1)

0.71 (0.25–0.95)

3.65a (1.17–6.1)

< 0.001

 

Range

(0.01–2.99)

(0.12–8.6)

(0.07–1.1

0.5–8.4)

 
  1. *Highly significant difference with group 1 (P = 0.005)
  2. **Significant difference with group 1 (P = 0.043)
  3. ***Highly significant difference with group 1 (P = 0.004)
  4. aHighly significant difference with group 1 (P < 0001)
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