The Egyptian Heart Journal

Table 4 Predictive value of miR-21, miR-124 and endoglin for type 1 PH

From: Role of micro-RNAs 21, 124 and other novel biomarkers in distinguishing between group 1 WHO pulmonary hypertension and group 2, 3 WHO pulmonary hypertension

	Cut off point	AUC	Sensitivity	Specificity	PPV	NPV
miRNA21	≥ 1.55 µM	0.742	60.0	95.0	94.7	61.3
miRNA124	≤ 1.58 µM	0.789	86.7	75.0	83.9	78.9
Endoglin	> 1.5 ng/ml	0.94	93.33	95.00	96.60	90.50

AUC, area under the curve; PPV, positive predictive value; NPV, negative predictive value

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