Articles

Cardiovascular autonomic neuropathy in people with type 2 diabetes mellitus; investigation of its association with classical cardiovascular risk factors using cardiovascular autonomic reflex tests: a cross-sectional study

People with type 2 diabetes mellitus (DM) are at increased risk of cardiovascular disease (CVD). Cardiovascular autonomic neuropathy (CAN) is an underdiagnosed risk factor for CVD, which is prevalent among peo...

Authors: Ahmad Osailan

Spontaneous pulmonary artery thrombus in a neonate

Pulmonary artery thrombosis is rare in neonates and mimics as persistent pulmonary hypertension or congenital heart disease. Risk factors include septicemia, dehydration, polycythemia, maternal diabetes, asphy...

Authors: Y. S. Shrimanth, Krishna Prasad, Adari Appala Karthik, Parag Barwad, C. R. Pruthvi, Atit A. Gawalkar, Krishna Santosh and Sanjeev Naganur

Safety and efficacy outcomes at 1 year after MitraClip therapy for percutaneous mitral valve repair in patients with severe mitral regurgitation: the Egyptian experience

Our aim was to assess safety and efficacy outcomes at 1 year after MitraClip for percutaneous mitral valve repair in patients with severe mitral regurgitation.

Authors: Radwa Abdullah Elbelbesy, Ahmed Mohsen Elsawah, Ahmed Shafie Ammar, Hazem Abdelmohsen Khamis and Islam Elsayed Shehata

Rivaroxaban versus warfarin for the management of left ventricle thrombus

Rivaroxaban has been recently introduced for the management of non-valvular intra-cardiac thrombosis with variable results. We aimed to compare the results of the off-label use of rivaroxaban versus warfarin i...

Authors: Monirah A. Albabtain, Yahya Alhebaishi, Ola Al-Yafi, Hatim Kheirallah, Adel Othman, Haneen Alghosoon, Amr A. Arafat and Ahmed Alfagih

Anemia is a novel predictor for clinical ISR following PCI

Conflicting data were found regarding the anemia’s effect on percutaneous coronary intervention (PCI) outcomes. We directed our study to investigate anemia’s effect on clinical in-stent restenosis (ISR) follow...

Authors: Ahmed Hussein, Mohammad Shafiq Awad, Ahlam M. Sabra and Hossam Eldin M. Mahmoud

A rare presentation of an elderly patient with acute lymphocytic leukemia and platelet count of zero associated with ST-elevation myocardial infarction, pulmonary thromboembolism in the setting of SARS-CoV 2: a case report

Novel coronavirus disease 2019 (COVID-19) is known to lead not only to severe acute respiratory syndrome, but also can result in thromboembolic events in both the venous and the arterial circulation by inducin...

Authors: Arash Hashemi, Fady Gerges, Haseeb Raza Naqvi, Irina Kotlar, Sara Moscatelli, Ashkan Hashemi, Yasmin Rustamova and Abdallah Almaghraby

Clinical characteristics and outcomes of patients admitted with acute heart failure: insights from a single-center heart failure registry in South India

The epidemiology of HF in India is largely unexplored. Current resources are based on a few hospital-based and a community-based registry from North India. Thus, we present the data from a single hospital-base...

Authors: Aashiq Ahamed Shukkoor, Nimmy Elizabeth George, Shanmugasundaram Radhakrishnan, Sivakumar Velusamy, Rajendiran Gopalan, Tamilarasu Kaliappan, Premkrishna Anandan, Ramasamy Palanimuthu, Vidhyakar Balasubramaniam, Vinoth Doraiswamy and Arun Kaushik Ponnusamy

Excess epicardial fat volume in women is a novel risk marker for microvascular dysfunction, which may be a contributing factor in the atypical chest pain syndrome

Excess epicardial fat volume (EFV) has been recently implicated in cardiovascular structural and functional abnormalities. It has been associated with abnormal microvascular stiffness (as reflected by radial a...

Authors: Mahfouz El Shahawy, Susan Tucker, Lillee Izadi, Antonella Sabatini and Sukanya Mohan

Incidence and impact of totally occluded culprit coronary artery in patients with non-ST segment elevation myocardial infarction acute coronary syndrome

Significance of totally occluded culprit coronary artery in patients presenting with non-ST segment elevation myocardial infarction (NSTEMI) is underestimated. The aim of the study was to evaluate the incidenc...

Authors: Sherif W. Ayad, Tarek H. El Zawawy, Mohamed I. Lotfy, Ahmed M. Naguib and Ahmed M. El Amrawy

Predicting the outcome in confirmed COVID-19 patients with coronary artery disease: a key role for the first chest computed tomography

Serial chest computed tomography (CT) scans are used to detect coronavirus disease 2019 (COVID-19) pneumonia and monitor the disease course. This study investigates relationship between total severity score by...

Authors: Negar Omidi, Masoumeh Lotfi-Tokaldany, Shapour Shirani, Mojtaba Salarifar, Hamidreza Poorhosseini, Seyyed Mojtaba Ghorashi and Afsaneh Aein

Coronary tortuosity relation with carotid intima-media thickness, coronary artery disease risk factors, and diastolic dysfunction: is it a marker of early atherosclerosis?

Coronary tortuosity (C-Tor) is a common finding in coronary angiography (CAG). There are conflicting data about its link to atherosclerosis: one study found a negative relationship with coronary artery disease...

Authors: Ahmed Elamragy, Samuel Yakoub, Mohamed AbdelGhany and Waleed Ammar

Non-ST elevation acute coronary syndromes; clinical landscape, management strategy and in-hospital outcomes: an age perspective

As the elderly represent a substantial proportion of medical care beneficiaries, and there is limited data about age disparity in emerging countries, this study sought to investigate the impact of age on the m...

Authors: Zainab Atiyah Dakhil and Hasan Ali Farhan

The comparison of serum TGF-beta levels and associated polymorphisms in patients with coronary artery ectasia and normal coronary artery

Coronary artery ectasia (CAE) is described as the enlargement of a coronary artery segment by 1.5 times or more, which is generally associated with the atherosclerotic process. Atherosclerotic changes lead to ...

Authors: Özgür Selim Ser, Gökhan Çetinkal, Onur Kiliçarslan, Yalçın Dalgıç, Servet Batit, Kudret Keskin, Gulçin Özkara, Ezgi Irmak Aslan, Hülya Yilmaz Aydoğan, Ahmet Yıldız and Zerrin Yiğit

Cardiac rehabilitation via telerehabilitation in COVID-19 pandemic situation

Adherence to medication and lifestyle changes are very important in the secondary prevention of cardiovascular disease. One of the ways is by doing a cardiac rehabilitation program.

Authors: Dian M. Sari and Laurentia C. G. Wijaya

Percutaneous management of reperfusion arrhythmias during primary percutaneous coronary intervention: a case report

Myocardial reperfusion may cause profound electrophysiological alterations and can lead to serious reperfusion arrhythmias (RA). Management of RA and the accompanying electrical storm that may occur remains a ...

Authors: Hesham Salah El Din Taha and Mirna Mamdouh Shaker

Evaluation of cardiomyopathy diagnosis in heart transplant recipients: comparison of echocardiographic and pathologic classification

Definite diagnosis of cardiomyopathy types can be challenging in end-stage disease process. New growing data have suggested that there is inconsistency between echocardiography and pathology in defining type o...

Authors: Neda Behzadnia, Babak Sharif-Kashani, Zargham Hossein Ahmadi, Farah Naghashzadeh, Atosa Dorudinia, Alireza Jahangirifard, Hamoun Hamarz and Payam Abbasi

PR interval as a predictor of syncope in tilt-up testing in adolescents and young adults

Syncope, as the most frequent consciousness disorder, is very common in young individuals. The aim of this study was to analyze ECG parameters and clinical properties obtained during tilt-up testing in 12 to 3...

Authors: Juraj Jug, Lada Bradić, Rea Levicki and Martina Lovrić Benčić

Physiological pacing to improve cardiac resynchronization therapy non-responder and a tryst with calcified septum—a case report

As per the literature, patients with intraventricular conduction delay (IVCD) do not respond well to cardiac resynchronization therapy (CRT) alone. They need advanced technological approach and out of the box ...

Authors: Vanita Arora, Francesco Zanon, Viveka Kumar, Vivek Kumar and Pawan Suri

Will introduction of ARNI reduce the need of device therapy in heart failure with reduced ejection fraction?

Authors: Navjyot Kaur, CR Pruthvi and Manojkumar Rohit

Subtle right ventricular dysfunction in asymptomatic chronic heavy cigarette smokers: a speckle tracking case-control study

Chronic heavy cigarette smoking can affect the right ventriclular function. The standard echocardiography may not show early right ventricular functional changes, and a more sensitive measure is needed. The ai...

Authors: Mohammad Iqbal Janhangeer, Ghada Youssef, Weal El Naggar and Dalia El Remisy

The relation between ApoB/ApoA-1 ratio and the severity of coronary artery disease in patients with acute coronary syndrome

Apolipoprotein B is considered the primary protein constituent of low-density lipoprotein. LDL contains variable quantities of cholesterol, but each lipoprotein contains a single ApoB protein. Thus, ApoB is a ...

Authors: Rehab Ibrahim Yaseen, Mohamed Hesham El-Leboudy and Hend Mohammed El-Deeb

Multimodality imaging of an interventricular septum hydatid cyst

Cardiac hydatid over the interventricular septum is extremely rare. Echinococcus infests humans as an accidental host. Echocardiography usually clinches the diagnosis of cardiac hydatid. However, multimodality...

Authors: Krishna Prasad, Rupesh Kumar, Vikram Halder, Muni Raju, Sunder Lal Negi and Sanjeev Naganur

Prognostic value of GRACE score for in-hospital and 6 months outcomes after non-ST elevation acute coronary syndrome

The aim of this study was to determine the predictive value of the Global Registry of Acute Coronary Events (GRACE) score for predicting in-hospital and 6 months mortality after non-ST elevation acute coronary...

Authors: Dileep Kumar, Arti Ashok, Tahir Saghir, Naveedullah Khan, Bashir Ahmed Solangi, Tariq Ahmed, Musa Karim, Khadijah Abid, Reeta Bai, Rekha Kumari and Hitesh Kumar

Multidisciplinary assessment of patients with ischemic stroke, the structure of a stroke team, and first Egyptian experience in adults undergoing transcatheter PFO closure for PFO-related stroke

Patent foramen ovale closure in the setting of stroke was debatable until the recent data from the long-term follow-up of multiple randomized control trials. These recent data have led to increase the number o...

Authors: Amr Mansour, Noha M. Gamal, Azza A. Elfiky, Mohamed Ayman Saleh, Samia Ashour Mohamed, Hala Mahmoud ElKhawas, Ahmed ElSadek, Noha L. Dawood and Maiy H. Elsayed

The combined role of NT-proBNP and LV-GLS in the detection of early subtle chemotherapy-induced cardiotoxicity in breast cancer female patients

Chemotherapeutic agents have many side effects; among them is cardiotoxicity. Ejection fraction fails to detect the subtle alterations of left ventricular (LV) function; that is why there is a need for a more ...

Authors: Laila Sulaiman, Dina Hesham, Magdy Abdel Hamid and Ghada Youssef

Study of the relation between serum levels of long-acting penicillin and the inflammatory markers: C-reactive protein and interleukin-6 in patients with chronic rheumatic heart disease

There is an evidence of a chronic inflammatory state in patients with chronic rheumatic valvular heart disease (RHD) as shown by high serum levels of high-sensitivity C-reactive protein (hs-CRP) and interleuki...

Authors: Ahmad M. Yousef, Osama A. Rifaie, Mohamed A. Hamza and Sameh A. Amin

High-degree atrioventricular block. An unusual presentation of Takotsubo cardiomyopathy: a case report

Takotsubo cardiomyopathy is a non-ischemic cardiomyopathy characterized by acute left ventricular systolic dysfunction with transient wall motion abnormalities without a culprit coronary stenosis or other conc...

Authors: Pablo Revilla-Martí, Juan F. Cueva-Recalde, Jose A. Linares-Vicente, Sara Río-Sánchez and Jose R. Ruiz-Arroyo

Egyptian practical guidance in lipid management 2020

Numerous epidemiological investigations and randomized clinical studies have determined that dyslipidemia is a major contributor to atherosclerotic cardiovascular disease (ASCVD). Consequently, the management ...

Authors: Hesham Salah El Din Taha, Hala Mahfouz Badran, Hossam Kandil, Nabil Farag, Abbas Oraby, Magdy El Sharkawy, Khaled Shokry, Fouad Fawzy, Hossam Mahrous, Juliette Bahgat, Mina Samy and Mirna Mamdouh Shaker

Effects of cardiac pacemakers on left ventricular volumes and function assessed by 3D echocardiography, Doppler method, and global longitudinal strain

Many previous studies reported the negative effects of right ventricular (RV) pacing on the left ventricular (LV) structure and ejection fraction. Studying pacing hemodynamics is essential to understand these ...

Authors: Moustafa Dawood, Eman Elsharkawy, Mohamed Ayman Abdel-Hay and Moustafa Nawar

Acute vascular complications of femoral veno-arterial ECMO: a single-centre retrospective study

Femoral arterial cannulation to initiate veno-arterial ECMO may result in ipsilateral limb ischemia due to reduced distal blood flow below the insertion point of the cannula. We retrospectively studied adult p...

Authors: Mohamed Laimoud, Elias Saad and Samer Koussayer

Experience with the novel unifemoral parallel sheath technique in percutaneous intervention of chronic total coronary occlusions

Percutaneous interventions to address chronic coronary occlusions (CTO-PCI) often require simultaneous ipsi- and contralateral coronary injections. Although radial access is increasingly popular, bifemoral art...

Authors: Joerg Reifart, Konstanze Schilling, Christian W. Hamm and Nicolaus Reifart

Clinical outcome of renin-angiotensin-aldosterone system blockers in treatment of hypertensive patients with COVID-19: a systematic review and meta-analysis

Novel coronavirus disease 2019 has been stated as global disease pandemic due to its rapid spread worldwide. Up to 30% of coronavirus disease 2019 patients with hypertension are more susceptible to death. Angi...

Authors: Andrea Laurentius, Brian Mendel and Radityo Prakoso

Association between age and infection in patients with acute ST-elevation myocardial infarction

ST-elevation myocardial infarction (STEMI) in young patients has a unique risk profile. We aimed to detect bacteria in aspirate of infarct artery in young versus old patients.

Authors: Magdy Algowhary

Pattern of congenital heart disease among Egyptian children: a 3-year retrospective study

Congenital heart disease (CHD) is a multifactorial birth defect which has variable demographic characteristics among children in different geographical areas. This study aimed to detect the distribution of dem...

Authors: Marwa Moustapha Al-Fahham and Yasmin Abdelrazek Ali

Predictors of pacing induced left ventricular dysfunction and cardiomyopathy assessed by three-dimensional echocardiography and speckle tracking strain

Long-term RV pacing leads to ventricular dyssynchrony, in the form of LBBB-like morphology, with subsequent detrimental effects on LV structure and function. Three-dimensional echocardiography allowed early de...

Authors: Moustafa Dawood, Eman Elsharkawy, Mohamed Ayman Abdel-Hay and Moustafa Nawar

The relationship of the serum endocan level with the CHA₂DS₂-VASc score in patients with paroxysmal atrial fibrillation

In this study considering the relationship between serum endocan and CHA₂DS₂-VASc score, we assumed that endocan level could be a new biomarker for stroke risk in patients with paroxysmal atrial fibrillation (PAF...

Authors: Gökhan Ceyhun

Outcome of manual thrombus aspiration for patients undergoing primary PCI for acute STEMI showing large thrombus burden

Routine thrombus aspiration during primary PCI does not improve clinical outcomes. Although recent guidelines for management of patient presented by ST-elevation myocardial infarction treated by primary PCI do...

Authors: Ehab Mohamed Elfekky, Michael Nabil Penjameen, Ahmed Ibrahim Nassar and Ramy Raymond Elias

Effect of discontinuation of ticagrelor and switching-over to other P2Y12 agents in patients with acute coronary syndrome: a single-center real-world experience from India

Dual antiplatelet therapy is the current standard of care after acute coronary syndrome (ACS) and percutaneous coronary intervention (PCI). We intended to study the pattern of use of ticagrelor in patients wit...

Authors: Nagendra Boopathy Senguttuvan, Ramesh Sankaran, Yashasvi Rajeev, Devi Thaiyal, Angel Mathew, K. Dharsini, Divya Marcelene, Maria Jusler Kalsingh, Sujit Kumar Sahu, Aravind Sampath, K. J. Prem Kumar, Harikrishnan Parthasarathy, Amal Louis, Anand Gnanaraj, K. N. Reddy and K. A. Abraham

Global longitudinal strain as a predictor of short-term effect of oral antiviral regimens on myocardium in Egyptian patients with chronic viral hepatitis C

Hepatitis C virus (HCV) infection has been noted with various cardiovascular (CV) diseases, and patients with detected HCV-RNA had higher CV mortality than uninfected individuals. The new direct-acting antivir...

Authors: Hazem Mohammad-Ali Farrag, Mina Samir Monir, Wael Soliman Abdel-Dayem, Hisham Abdel-Haleem Ali and Alaa Mohammad Ibrahim

Can QT dispersion improve the accuracy of stress ECG TMT in detecting myocardial ischemia in chronic stable CAD patients? A stress myocardial perfusion imaging study

QT dispersion (QTd) is related to regional variations in myocardial repolarization. Our study aims to assess the value of QTd in prediction of myocardial ischemia and its severity during stress imaging.

Authors: Mohammad Abdalla Eltahlawi, Ahmed Mohamed Sanad, Kamel Hasan Ghazal and Ahmed Taha Abdelwahed

Effect of a phase 2 cardiac rehabilitation program on obese and non-obese patients with stable coronary artery disease

Obesity is associated with significant cardiovascular morbidity and mortality effects. Cardiac rehabilitation programs cause a significant reduction in cardiovascular mortality and a reduction in all cardiovas...

Authors: Ahmed El Missiri, Walaa Adel Abdel Halim, Abdo Saleh Almaweri and Tarek Rashid Mohamed

Routine pre-employment echocardiography assessment in young adults: cost and benefits

Conventional echocardiography is a safe, available, and accurate tool for cardiac structural and functional evaluation, but it should not cancel clinical assessment and history tacking, and indeed both are com...

Authors: Ahmed Gaafar and Asmaa Gaafar

COVID-19 lockdown may increase cardiovascular disease risk factors

Coronavirus disease 2019 (COVID-19) is a disease caused by severe acute respiratory syndrome coronavirus 2 (SARS CoV-2) and was declared a worldwide pandemic by the World Health Organization (WHO) on 11 March ...

Authors: Daha Garba Muhammad and Ibrahim Ahmad Abubakar

Acute coronary syndrome: which age group tends to delay call for help?

Early diagnosis and treatment of ACS can reduce the risk of complications and death. Delay calling for help can increase morbidity and mortality. It is unclear which age group among patients with acute coronar...

Authors: Ahmed Ayuna and Ayyaz Sultan

Retraction Note: Association of severity of coronary artery disease by SYNTAX score (SS) and lower extremity arterial disease by duplex ultrasound (DUS) study—an Indian perspective

This article has been retracted. Please see the Retraction Notice for more detail: https://doi.org/10.1186/s43044-020-00091-z.

Authors: Saumen Nandi, Anindya Mukherjee, Dibbendhu Khanra and Kaushik Biswas

Correction to: Association of culprit lesion plaque characteristics with flow restoration post-fibrinolysis in ST-segment elevation myocardial infarction: an intravascular ultrasound-virtual histology study

An amendment to this paper has been published and can be accessed via the original article.

Authors: Raghavendra Rao K, Sreenivas Reddy, Jeet Ram Kashyap, Vadivelu Ramalingam, Debabrata Dash, Vikas Kadiyala, Suraj Kumar, Hithesh Reddy, Jaspreet Kaur, Ashok Kumar, Naindeep Kaur and Anish Gupta

Clinical outcomes of submassive pulmonary embolism thrombolysis—an Indian experience

Acute pulmonary thromboembolism is the most dangerous presentation of venous thromboembolic disease. The role of thrombolysis in massive pulmonary embolism has been studied extensively, but the same is not the...

Authors: Nadeem U. Rehman, Mohd Iqbal Dar, Manish Bansal and R. R. Kasliwal

Association of culprit lesion plaque characteristics with flow restoration post-fibrinolysis in ST-segment elevation myocardial infarction: an intravascular ultrasound-virtual histology study

Not every patient achieves normal coronary flow following fibrinolysis in STEMI (ST-segment elevation myocardial infarction). The culprit lesion plaque characteristics play a prominent role in the coronary flo...

Authors: Raghavendra Rao K, Sreenivas Reddy, Jeet Ram Kashyap, Vadivelu Ramalingam, Debabrata Dash, Vikas Kadiyala, Suraj Kumar, Hithesh Reddy, Jaspreet Kaur, Ashok Kumar, Naindeep Kaur and Anish Gupta

The changes in biventricular remodelling and function after atrial septal defect device closure and its relation to age of closure

The trans-catheter closure of atrial septal defect (ASD) usually has a rapid impact on biventricular remodelling and functions. Whether the transcatheter closure of ASD at early childhood or at adulthood age w...

Authors: Areej Alkhateeb, Alaa Roushdy, Hosam Hasan-Ali, Yehia Taha Kishk and Ayman K. M. Hassan

Cardiac catheterization addressing early post-operative complications in congenital heart surgery—a single-center experience

Cardiac catheterization after congenital heart surgery may play an important role in the diagnosis and management of patients with a complicated or unusual post-operative course. The main objective of this stu...

Authors: Saud Bahaidarah, Jameel Al-Ata, Gaser Abdelmohsen, Naif Alkhushi, Mohamed Abdelsalam, Mohammed Mujahed, Osman Al-Radi, Ahmed Elassal, Zaher Zaher, Ahmad Azhar and Ahmed M. Dohain